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Identifying modifiable behavioral factors affecting cancer risk among persons living with HIV or AIDS (PLWHA) could help to explain this rise in cancer burden and guide the development of prevention strategies targeting these factors. The rising incidence of non-AIDS-defining malignancies (non-ADMs) among HIV-infected individuals in the HAART era is not fully explained by improvement in HAART regimens or traditional risk factors such as immunodeficiency, aging, and smoking.

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